Blood Test Glossary
Plain-English explanations for 36+ common blood markers — what they measure, what normal ranges mean, and why they matter for your health.
Complete Blood Count (CBC)
Hemoglobin
Hgb / HbCBCThe protein in red blood cells that carries oxygen from your lungs to the rest of your body. It is the most important indicator of anemia.
Normal Range
Men: 13.5–17.5 · Women: 12–15.5 g/dL
If High ↑
Polycythemia, dehydration, smoking, high altitude
If Low ↓
Anemia (iron deficiency, B12/folate deficiency, chronic disease, blood loss)
White Blood Cells
WBC / LeukocytesCBCImmune cells that defend the body against infection and disease. An elevated count usually signals infection or inflammation.
Normal Range
4,500–11,000 cells/µL
If High ↑
Infection, inflammation, leukemia, stress, steroid use
If Low ↓
Viral illness, bone marrow problems, autoimmune disorders, chemotherapy
Platelets
PLTCBCTiny cells that clump together to form blood clots and stop bleeding. Critical for wound healing.
Normal Range
150,000–400,000 /µL
If High ↑
Thrombocytosis: iron deficiency, infection, inflammatory disease
If Low ↓
Thrombocytopenia: bleeding risk, autoimmune disease, bone marrow suppression
Hematocrit
HctCBCThe percentage of blood volume made up of red blood cells. Closely related to hemoglobin.
Normal Range
Men: 41–53% · Women: 36–46% %
If High ↑
Dehydration, polycythemia
If Low ↓
Anemia, overhydration
Mean Corpuscular Volume
MCVCBCAverage size of red blood cells. Helps classify the type of anemia when hemoglobin is low.
Normal Range
80–100 fL
If High ↑
Macrocytic anemia: B12/folate deficiency, liver disease, hypothyroidism
If Low ↓
Microcytic anemia: iron deficiency, thalassemia
Neutrophils
NEUTCBCThe most common type of white blood cell, the first responders to bacterial infections.
Normal Range
1,800–7,700 cells/µL
If High ↑
Bacterial infection, physical stress, steroid use
If Low ↓
Neutropenia: viral infection, chemotherapy, autoimmune disease
Lymphocytes
LYMPHCBCWhite blood cells that include T-cells and B-cells — the core of adaptive immunity.
Normal Range
1,000–4,800 cells/µL
If High ↑
Viral infections, lymphoma, chronic lymphocytic leukemia
If Low ↓
HIV/AIDS, steroid use, chemotherapy, stress
Lipid Panel
Total Cholesterol
TCLipidsSum of all cholesterol in the blood. High levels increase the risk of heart disease and stroke.
Normal Range
< 200 (desirable) mg/dL
If High ↑
Increased cardiovascular risk, familial hypercholesterolemia, hypothyroidism
If Low ↓
Malnutrition, hyperthyroidism, liver disease (rarely symptomatic)
LDL Cholesterol
LDL-CLipidsOften called "bad" cholesterol. LDL deposits cholesterol in artery walls, leading to plaque and cardiovascular disease.
Normal Range
< 100 (optimal) · < 130 (near optimal) mg/dL
If High ↑
Atherosclerosis, heart attack risk, stroke risk
If Low ↓
Generally favorable; below 40 may indicate malnutrition
HDL Cholesterol
HDL-CLipids"Good" cholesterol that transports excess cholesterol back to the liver for removal. Higher levels are protective.
Normal Range
Men: > 40 · Women: > 50 · Optimal: > 60 mg/dL
If High ↑
Generally protective; rarely above 100 (consider CETP deficiency)
If Low ↓
Increased cardiovascular risk, metabolic syndrome, diabetes
Triglycerides
TGLipidsBlood fats derived from dietary fat and excess calories. Elevated levels are linked to heart disease and pancreatitis.
Normal Range
< 150 (normal) · 150–199 (borderline high) mg/dL
If High ↑
Metabolic syndrome, diabetes, pancreatitis risk, alcohol use, high-carb diet
If Low ↓
Generally favorable; below 50 may indicate malnutrition or hyperthyroidism
Thyroid Panel
Thyroid Stimulating Hormone
TSHThyroidThe pituitary gland hormone that controls thyroid function. The most sensitive test for thyroid disorders.
Normal Range
0.4–4.0 mIU/L
If High ↑
Hypothyroidism (underactive thyroid): fatigue, weight gain, cold intolerance
If Low ↓
Hyperthyroidism (overactive thyroid): anxiety, weight loss, heat intolerance
Free Thyroxine
Free T4ThyroidThe active, unbound form of the main thyroid hormone. Confirms thyroid dysfunction when TSH is abnormal.
Normal Range
0.8–1.8 ng/dL
If High ↑
Hyperthyroidism, thyroiditis, excess thyroid medication
If Low ↓
Primary or secondary hypothyroidism
Free Triiodothyronine
Free T3ThyroidThe most biologically active thyroid hormone. Helps evaluate hyperthyroidism and thyroid conversion disorders.
Normal Range
2.3–4.2 pg/mL
If High ↑
T3 toxicosis, hyperthyroidism
If Low ↓
Hypothyroidism, low T4-to-T3 conversion (selenium deficiency)
Metabolic Panel
Glucose (Fasting)
GLUMetabolicBlood sugar level measured after an 8+ hour fast. The primary screen for diabetes and prediabetes.
Normal Range
70–99 (normal) · 100–125 (prediabetes) mg/dL
If High ↑
Diabetes (≥ 126), prediabetes (100–125), stress hyperglycemia
If Low ↓
Hypoglycemia: excess insulin, fasting, alcohol, adrenal insufficiency
HbA1c
Glycated HemoglobinMetabolicReflects average blood sugar over the past 2–3 months. The gold standard for diabetes monitoring.
Normal Range
< 5.7% (normal) · 5.7–6.4% (prediabetes) %
If High ↑
Diabetes (≥ 6.5%), poor glycemic control, increased complication risk
If Low ↓
Excellent glycemic control; below 4% may indicate hemolytic anemia
Sodium
Na⁺MetabolicRegulates fluid balance and nerve/muscle function. Critically controlled by the kidneys.
Normal Range
136–145 mEq/L
If High ↑
Hypernatremia: dehydration, diabetes insipidus, excess sodium intake
If Low ↓
Hyponatremia: heart failure, SIADH, excessive water intake
Potassium
K⁺MetabolicEssential for heart rhythm and muscle contraction. Even small deviations can be dangerous.
Normal Range
3.5–5.0 mEq/L
If High ↑
Hyperkalemia: kidney failure, ACE inhibitors, Addison's disease — cardiac risk
If Low ↓
Hypokalemia: cardiac arrhythmia risk, diuretic use, vomiting, diarrhea
Creatinine
CrMetabolicWaste product from muscle metabolism. Elevated levels indicate impaired kidney filtration.
Normal Range
Men: 0.7–1.3 · Women: 0.6–1.1 mg/dL
If High ↑
Acute kidney injury, chronic kidney disease, dehydration, high muscle mass
If Low ↓
Low muscle mass, malnutrition, late pregnancy
eGFR
Estimated Glomerular Filtration RateMetabolicCalculated estimate of how well kidneys filter blood per minute. The best overall kidney function test.
Normal Range
> 90 (normal) · 60–89 (mildly reduced) mL/min/1.73m²
If High ↑
Normal or above — sometimes seen with high muscle mass or hyperfiltration
If Low ↓
CKD staging: 15–29 severely reduced, < 15 kidney failure
Liver Panel
Alanine Aminotransferase
ALTLiverLiver enzyme most specific to liver damage. The primary marker for hepatitis, fatty liver, and drug-induced liver injury.
Normal Range
Men: 7–56 · Women: 7–45 U/L
If High ↑
Liver inflammation: hepatitis, NAFLD, alcohol, medications, celiac disease
If Low ↓
Generally favorable; very low in advanced liver disease
Aspartate Aminotransferase
ASTLiverLiver enzyme also found in heart and muscle. An AST:ALT ratio > 2 suggests alcoholic liver disease.
Normal Range
10–40 U/L
If High ↑
Liver damage, muscle injury, heart attack, hemolysis
If Low ↓
Generally favorable
Alkaline Phosphatase
ALPLiverEnzyme from liver, bile ducts, and bone. Elevated in bile duct obstruction and bone disorders.
Normal Range
44–147 U/L
If High ↑
Bile duct obstruction, bone disease, liver disease, Paget's disease
If Low ↓
Hypothyroidism, pernicious anemia, zinc deficiency
Bilirubin (Total)
T. BiliLiverYellow pigment from red blood cell breakdown. High levels cause jaundice (yellow skin/eyes).
Normal Range
0.1–1.2 mg/dL
If High ↑
Liver disease, bile duct obstruction, hemolysis, Gilbert syndrome
If Low ↓
Generally not clinically significant
Albumin
AlbLiverMajor protein made by the liver. Reflects liver's synthetic capacity and nutritional status.
Normal Range
3.5–5.0 g/dL
If High ↑
Dehydration
If Low ↓
Liver disease, malnutrition, kidney disease (protein loss), inflammation
Vitamins & Minerals
Vitamin D (25-OH)
25(OH)DVitaminsThe storage form of vitamin D. Produced in skin from sunlight and obtained from food. Critical for bone health, immunity, and mood.
Normal Range
30–100 (sufficient) · 20–29 (insufficient) ng/mL
If High ↑
Toxicity (> 150): hypercalcemia, nausea, kidney stones
If Low ↓
Deficiency (< 20): bone pain, fatigue, muscle weakness, immune dysfunction, depression
Vitamin B12
CobalaminVitaminsEssential for nerve function, DNA synthesis, and red blood cell formation. Only found naturally in animal products.
Normal Range
200–900 pg/mL
If High ↑
Rarely concerning; possible liver disease or myeloproliferative disorder
If Low ↓
Deficiency: macrocytic anemia, peripheral neuropathy, cognitive decline (vegans at risk)
Ferritin
FerrVitaminsIron storage protein. The most sensitive marker of iron deficiency before anemia develops.
Normal Range
Men: 30–400 · Women: 13–150 ng/mL
If High ↑
Iron overload, inflammation, liver disease, hemochromatosis
If Low ↓
Iron depletion/deficiency: fatigue, hair loss, restless legs syndrome
Folate
Vitamin B9VitaminsB-vitamin essential for DNA synthesis and cell division. Critical during pregnancy to prevent neural tube defects.
Normal Range
> 3.0 ng/mL
If High ↑
Generally not harmful; may mask B12 deficiency
If Low ↓
Megaloblastic anemia, elevated homocysteine, neural tube defect risk in pregnancy
Magnesium
MgVitaminsMineral involved in 300+ enzymatic reactions. Important for heart rhythm, muscle, nerve, and glucose metabolism.
Normal Range
1.7–2.2 mg/dL
If High ↑
Hypermagnesemia: usually from supplements or kidney failure — muscle weakness
If Low ↓
Hypomagnesemia: muscle cramps, arrhythmias, anxiety, insulin resistance
Diabetes Markers
Fasting Insulin
InsDiabetesBaseline insulin level. High fasting insulin is an early sign of insulin resistance, often before blood sugar rises.
Normal Range
2–25 µIU/mL
If High ↑
Insulin resistance, metabolic syndrome, prediabetes, PCOS
If Low ↓
Type 1 diabetes, hypoglycemia, low carbohydrate intake
C-Peptide
C-PepDiabetesProduced equally with insulin by the pancreas. Distinguishes Type 1 from Type 2 diabetes and evaluates insulin production.
Normal Range
0.5–2.0 nmol/L
If High ↑
Type 2 diabetes, insulin resistance, insulinoma
If Low ↓
Type 1 diabetes, insulin therapy reducing endogenous production
Inflammation & Cardiac
C-Reactive Protein (High Sensitivity)
hs-CRPInflammationMarker of systemic inflammation. The high-sensitivity test predicts cardiovascular risk independent of cholesterol.
Normal Range
< 1.0 (low risk) · 1.0–3.0 (moderate risk) mg/L
If High ↑
Infection, autoimmune disease, cardiovascular risk, metabolic syndrome
If Low ↓
Favorable: low inflammation state
Homocysteine
HcyInflammationAmino acid that damages blood vessel walls at high levels. Elevated by low B6, B12, and folate.
Normal Range
5–15 µmol/L
If High ↑
Cardiovascular risk, stroke risk, B-vitamin deficiency, kidney disease
If Low ↓
Generally favorable
Troponin I or T
cTnI / cTnTCardiacProteins released from damaged heart muscle. The most sensitive and specific markers of heart attack.
Normal Range
< 0.04 (cTnI) · < 0.01 (cTnT) ng/mL
If High ↑
URGENT: Heart attack, myocarditis, pulmonary embolism, heart failure
If Low ↓
Normal — no acute cardiac injury
Brain Natriuretic Peptide
BNP / NT-proBNPCardiacReleased by stressed heart ventricles. Key marker for diagnosing and monitoring heart failure severity.
Normal Range
BNP: < 100 · NT-proBNP: < 300 pg/mL
If High ↑
Heart failure, fluid overload, pulmonary hypertension
If Low ↓
Normal cardiac function; obesity can falsely lower levels
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