Medical Reference Guide

Blood Test Glossary

Plain-English explanations for 36+ common blood markers — what they measure, what normal ranges mean, and why they matter for your health.

⚕️Medical disclaimer: Reference ranges vary by laboratory, age, sex, and clinical context. This glossary is for educational purposes only. Always discuss your specific results with a qualified healthcare professional.

Complete Blood Count (CBC)

Hemoglobin

Hgb / HbCBC

The protein in red blood cells that carries oxygen from your lungs to the rest of your body. It is the most important indicator of anemia.

Normal Range

Men: 13.5–17.5 · Women: 12–15.5 g/dL

If High ↑

Polycythemia, dehydration, smoking, high altitude

If Low ↓

Anemia (iron deficiency, B12/folate deficiency, chronic disease, blood loss)

White Blood Cells

WBC / LeukocytesCBC

Immune cells that defend the body against infection and disease. An elevated count usually signals infection or inflammation.

Normal Range

4,500–11,000 cells/µL

If High ↑

Infection, inflammation, leukemia, stress, steroid use

If Low ↓

Viral illness, bone marrow problems, autoimmune disorders, chemotherapy

Platelets

PLTCBC

Tiny cells that clump together to form blood clots and stop bleeding. Critical for wound healing.

Normal Range

150,000–400,000 /µL

If High ↑

Thrombocytosis: iron deficiency, infection, inflammatory disease

If Low ↓

Thrombocytopenia: bleeding risk, autoimmune disease, bone marrow suppression

Hematocrit

HctCBC

The percentage of blood volume made up of red blood cells. Closely related to hemoglobin.

Normal Range

Men: 41–53% · Women: 36–46% %

If High ↑

Dehydration, polycythemia

If Low ↓

Anemia, overhydration

Mean Corpuscular Volume

MCVCBC

Average size of red blood cells. Helps classify the type of anemia when hemoglobin is low.

Normal Range

80–100 fL

If High ↑

Macrocytic anemia: B12/folate deficiency, liver disease, hypothyroidism

If Low ↓

Microcytic anemia: iron deficiency, thalassemia

Neutrophils

NEUTCBC

The most common type of white blood cell, the first responders to bacterial infections.

Normal Range

1,800–7,700 cells/µL

If High ↑

Bacterial infection, physical stress, steroid use

If Low ↓

Neutropenia: viral infection, chemotherapy, autoimmune disease

Lymphocytes

LYMPHCBC

White blood cells that include T-cells and B-cells — the core of adaptive immunity.

Normal Range

1,000–4,800 cells/µL

If High ↑

Viral infections, lymphoma, chronic lymphocytic leukemia

If Low ↓

HIV/AIDS, steroid use, chemotherapy, stress

Lipid Panel

Total Cholesterol

TCLipids

Sum of all cholesterol in the blood. High levels increase the risk of heart disease and stroke.

Normal Range

< 200 (desirable) mg/dL

If High ↑

Increased cardiovascular risk, familial hypercholesterolemia, hypothyroidism

If Low ↓

Malnutrition, hyperthyroidism, liver disease (rarely symptomatic)

LDL Cholesterol

LDL-CLipids

Often called "bad" cholesterol. LDL deposits cholesterol in artery walls, leading to plaque and cardiovascular disease.

Normal Range

< 100 (optimal) · < 130 (near optimal) mg/dL

If High ↑

Atherosclerosis, heart attack risk, stroke risk

If Low ↓

Generally favorable; below 40 may indicate malnutrition

HDL Cholesterol

HDL-CLipids

"Good" cholesterol that transports excess cholesterol back to the liver for removal. Higher levels are protective.

Normal Range

Men: > 40 · Women: > 50 · Optimal: > 60 mg/dL

If High ↑

Generally protective; rarely above 100 (consider CETP deficiency)

If Low ↓

Increased cardiovascular risk, metabolic syndrome, diabetes

Triglycerides

TGLipids

Blood fats derived from dietary fat and excess calories. Elevated levels are linked to heart disease and pancreatitis.

Normal Range

< 150 (normal) · 150–199 (borderline high) mg/dL

If High ↑

Metabolic syndrome, diabetes, pancreatitis risk, alcohol use, high-carb diet

If Low ↓

Generally favorable; below 50 may indicate malnutrition or hyperthyroidism

Thyroid Panel

Thyroid Stimulating Hormone

TSHThyroid

The pituitary gland hormone that controls thyroid function. The most sensitive test for thyroid disorders.

Normal Range

0.4–4.0 mIU/L

If High ↑

Hypothyroidism (underactive thyroid): fatigue, weight gain, cold intolerance

If Low ↓

Hyperthyroidism (overactive thyroid): anxiety, weight loss, heat intolerance

Free Thyroxine

Free T4Thyroid

The active, unbound form of the main thyroid hormone. Confirms thyroid dysfunction when TSH is abnormal.

Normal Range

0.8–1.8 ng/dL

If High ↑

Hyperthyroidism, thyroiditis, excess thyroid medication

If Low ↓

Primary or secondary hypothyroidism

Free Triiodothyronine

Free T3Thyroid

The most biologically active thyroid hormone. Helps evaluate hyperthyroidism and thyroid conversion disorders.

Normal Range

2.3–4.2 pg/mL

If High ↑

T3 toxicosis, hyperthyroidism

If Low ↓

Hypothyroidism, low T4-to-T3 conversion (selenium deficiency)

Metabolic Panel

Glucose (Fasting)

GLUMetabolic

Blood sugar level measured after an 8+ hour fast. The primary screen for diabetes and prediabetes.

Normal Range

70–99 (normal) · 100–125 (prediabetes) mg/dL

If High ↑

Diabetes (≥ 126), prediabetes (100–125), stress hyperglycemia

If Low ↓

Hypoglycemia: excess insulin, fasting, alcohol, adrenal insufficiency

HbA1c

Glycated HemoglobinMetabolic

Reflects average blood sugar over the past 2–3 months. The gold standard for diabetes monitoring.

Normal Range

< 5.7% (normal) · 5.7–6.4% (prediabetes) %

If High ↑

Diabetes (≥ 6.5%), poor glycemic control, increased complication risk

If Low ↓

Excellent glycemic control; below 4% may indicate hemolytic anemia

Sodium

Na⁺Metabolic

Regulates fluid balance and nerve/muscle function. Critically controlled by the kidneys.

Normal Range

136–145 mEq/L

If High ↑

Hypernatremia: dehydration, diabetes insipidus, excess sodium intake

If Low ↓

Hyponatremia: heart failure, SIADH, excessive water intake

Potassium

K⁺Metabolic

Essential for heart rhythm and muscle contraction. Even small deviations can be dangerous.

Normal Range

3.5–5.0 mEq/L

If High ↑

Hyperkalemia: kidney failure, ACE inhibitors, Addison's disease — cardiac risk

If Low ↓

Hypokalemia: cardiac arrhythmia risk, diuretic use, vomiting, diarrhea

Creatinine

CrMetabolic

Waste product from muscle metabolism. Elevated levels indicate impaired kidney filtration.

Normal Range

Men: 0.7–1.3 · Women: 0.6–1.1 mg/dL

If High ↑

Acute kidney injury, chronic kidney disease, dehydration, high muscle mass

If Low ↓

Low muscle mass, malnutrition, late pregnancy

eGFR

Estimated Glomerular Filtration RateMetabolic

Calculated estimate of how well kidneys filter blood per minute. The best overall kidney function test.

Normal Range

> 90 (normal) · 60–89 (mildly reduced) mL/min/1.73m²

If High ↑

Normal or above — sometimes seen with high muscle mass or hyperfiltration

If Low ↓

CKD staging: 15–29 severely reduced, < 15 kidney failure

Liver Panel

Alanine Aminotransferase

ALTLiver

Liver enzyme most specific to liver damage. The primary marker for hepatitis, fatty liver, and drug-induced liver injury.

Normal Range

Men: 7–56 · Women: 7–45 U/L

If High ↑

Liver inflammation: hepatitis, NAFLD, alcohol, medications, celiac disease

If Low ↓

Generally favorable; very low in advanced liver disease

Aspartate Aminotransferase

ASTLiver

Liver enzyme also found in heart and muscle. An AST:ALT ratio > 2 suggests alcoholic liver disease.

Normal Range

10–40 U/L

If High ↑

Liver damage, muscle injury, heart attack, hemolysis

If Low ↓

Generally favorable

Alkaline Phosphatase

ALPLiver

Enzyme from liver, bile ducts, and bone. Elevated in bile duct obstruction and bone disorders.

Normal Range

44–147 U/L

If High ↑

Bile duct obstruction, bone disease, liver disease, Paget's disease

If Low ↓

Hypothyroidism, pernicious anemia, zinc deficiency

Bilirubin (Total)

T. BiliLiver

Yellow pigment from red blood cell breakdown. High levels cause jaundice (yellow skin/eyes).

Normal Range

0.1–1.2 mg/dL

If High ↑

Liver disease, bile duct obstruction, hemolysis, Gilbert syndrome

If Low ↓

Generally not clinically significant

Albumin

AlbLiver

Major protein made by the liver. Reflects liver's synthetic capacity and nutritional status.

Normal Range

3.5–5.0 g/dL

If High ↑

Dehydration

If Low ↓

Liver disease, malnutrition, kidney disease (protein loss), inflammation

Vitamins & Minerals

Vitamin D (25-OH)

25(OH)DVitamins

The storage form of vitamin D. Produced in skin from sunlight and obtained from food. Critical for bone health, immunity, and mood.

Normal Range

30–100 (sufficient) · 20–29 (insufficient) ng/mL

If High ↑

Toxicity (> 150): hypercalcemia, nausea, kidney stones

If Low ↓

Deficiency (< 20): bone pain, fatigue, muscle weakness, immune dysfunction, depression

Vitamin B12

CobalaminVitamins

Essential for nerve function, DNA synthesis, and red blood cell formation. Only found naturally in animal products.

Normal Range

200–900 pg/mL

If High ↑

Rarely concerning; possible liver disease or myeloproliferative disorder

If Low ↓

Deficiency: macrocytic anemia, peripheral neuropathy, cognitive decline (vegans at risk)

Ferritin

FerrVitamins

Iron storage protein. The most sensitive marker of iron deficiency before anemia develops.

Normal Range

Men: 30–400 · Women: 13–150 ng/mL

If High ↑

Iron overload, inflammation, liver disease, hemochromatosis

If Low ↓

Iron depletion/deficiency: fatigue, hair loss, restless legs syndrome

Folate

Vitamin B9Vitamins

B-vitamin essential for DNA synthesis and cell division. Critical during pregnancy to prevent neural tube defects.

Normal Range

> 3.0 ng/mL

If High ↑

Generally not harmful; may mask B12 deficiency

If Low ↓

Megaloblastic anemia, elevated homocysteine, neural tube defect risk in pregnancy

Magnesium

MgVitamins

Mineral involved in 300+ enzymatic reactions. Important for heart rhythm, muscle, nerve, and glucose metabolism.

Normal Range

1.7–2.2 mg/dL

If High ↑

Hypermagnesemia: usually from supplements or kidney failure — muscle weakness

If Low ↓

Hypomagnesemia: muscle cramps, arrhythmias, anxiety, insulin resistance

Diabetes Markers

Fasting Insulin

InsDiabetes

Baseline insulin level. High fasting insulin is an early sign of insulin resistance, often before blood sugar rises.

Normal Range

2–25 µIU/mL

If High ↑

Insulin resistance, metabolic syndrome, prediabetes, PCOS

If Low ↓

Type 1 diabetes, hypoglycemia, low carbohydrate intake

C-Peptide

C-PepDiabetes

Produced equally with insulin by the pancreas. Distinguishes Type 1 from Type 2 diabetes and evaluates insulin production.

Normal Range

0.5–2.0 nmol/L

If High ↑

Type 2 diabetes, insulin resistance, insulinoma

If Low ↓

Type 1 diabetes, insulin therapy reducing endogenous production

Inflammation & Cardiac

C-Reactive Protein (High Sensitivity)

hs-CRPInflammation

Marker of systemic inflammation. The high-sensitivity test predicts cardiovascular risk independent of cholesterol.

Normal Range

< 1.0 (low risk) · 1.0–3.0 (moderate risk) mg/L

If High ↑

Infection, autoimmune disease, cardiovascular risk, metabolic syndrome

If Low ↓

Favorable: low inflammation state

Homocysteine

HcyInflammation

Amino acid that damages blood vessel walls at high levels. Elevated by low B6, B12, and folate.

Normal Range

5–15 µmol/L

If High ↑

Cardiovascular risk, stroke risk, B-vitamin deficiency, kidney disease

If Low ↓

Generally favorable

Troponin I or T

cTnI / cTnTCardiac

Proteins released from damaged heart muscle. The most sensitive and specific markers of heart attack.

Normal Range

< 0.04 (cTnI) · < 0.01 (cTnT) ng/mL

If High ↑

URGENT: Heart attack, myocarditis, pulmonary embolism, heart failure

If Low ↓

Normal — no acute cardiac injury

Brain Natriuretic Peptide

BNP / NT-proBNPCardiac

Released by stressed heart ventricles. Key marker for diagnosing and monitoring heart failure severity.

Normal Range

BNP: < 100 · NT-proBNP: < 300 pg/mL

If High ↑

Heart failure, fluid overload, pulmonary hypertension

If Low ↓

Normal cardiac function; obesity can falsely lower levels

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